Current Research at the Institute for Reproductive Medicine and Science at Saint Barnabas

A number of research studies are currently underway at IRMS. All research activities at the Institute have been carefully reviewed and approved by the Institutional Review Board of the Saint Barnabas Medical Center. Prior to enrollment in any study protocol, patients are carefully counseled by the medical staff – no work is initiated without the clear consent of each patient. Treatment-based research initiatives at the Institute always involve the application of novel procedures or techniques that are expected, based on scientific principles or previous research, to benefit the participating patient. The purpose of this type of research is to scientifically prove that the new procedure is beneficial, and to determine the degree of benefit.

IVF Clinical Trial with IRMS

You may be eligible to participate in our study with PGS (Preimplantation Genetic Screening) if you meet the following criteria:

Are you currently trying to conceive and:

  • Are planning to do an IVF cycle?
  • Are between the ages of 25 and 40?
  • Have not had more than two failed IVF cycles?

IRMS is participating in a multi-center, international study designed to evaluate pregnancy outcomes in patients undergoing IVF with a Single Embryo Transfer (SET). The purpose of the study is to determine if biopsy and genetic testing of an embryo (PGS) results in a better outcome than the standard method of selecting an embryo based on how well it is growing in the lab.

In this study, there are two groups to which patients are assigned:

  • In one group, all the embryos that are developing normally 5 & 6 days after egg retrieval undergo screening for chromosomal abnormalities using a test called VeriSeq PGS. Participants will not be charged for the VeriSeq PGS.
  • In the other group, the best embryo is selected by standard screening methods and does not undergo VeriSeq PGS. All other embryos are tested with PGS.

Both groups have embryos frozen 5-6 days after the egg retrieval and will then undergo a frozen embryo transfer (FET):

  • Study participants will be offered a blood test after 10 weeks gestation called an NIPT test (Non-invasive Pre-Natal Testing) which will screen for chromosomal abnormalities commonly found in pregnancies such as Down Syndrome. Participants will not be charged for the NIPT test.

The benefits of the study are:

  • The embryos in both groups that have been tested but not transferred could be available for transfer in a future non-study cycle.
  • The study will help future patients know how much PGS (Preimplantation Genetic Screening) with VeriSeq improves their chances of having a healthy baby.

Your decision to participate in the study is entirely voluntary and deciding not to participate will not alter your care at IRMS.

To participate and/or for further information, please give us a call at 973-322-8286.

Download Trial Brochure